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Most studies of clinically considerable drug interactions transpiring with the barbiturates have concerned phenobarbital. Nonetheless, the appliance of such info to other barbiturates appears valid and warrants serial blood level determinations from the relevant drugs when there are numerous therapies.Corticosteroids. Barbiturates show up to enhanc

As with other sedatives and hypnotics, elderly or debilitated patients may possibly respond to barbiturates with marked pleasure, depression, or confusion. The systemic effects of exogenous hydrocortisone and endogenous hydrocortisone (cortisol) may be diminished by phenobarbital. Thus, this product or service should be administered with caution to